David H Vandorpe Selected Research

hereditary Xerocytosis

1/2019	Erythrocyte ion content and dehydration modulate maximal Gardos channel activity in KCNN4 V282M/+ hereditary xerocytosis red cells.
1/2017	Erythrocytes from hereditary xerocytosis patients heterozygous for KCNN4 V282M exhibit increased spontaneous Gardos channel-like activity inhibited by senicapoc.

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David H Vandorpe Research Topics

Disease

3	Nephrolithiasis 01/2016 - 03/2008
2	Sickle Cell Anemia (Hemoglobin S Disease) 01/2022 - 12/2021
2	Hypoxia (Hypoxemia) 01/2022 - 01/2010
2	hereditary Xerocytosis 01/2019 - 01/2017
2	Anemia 01/2014 - 05/2011
2	Autosomal Dominant Polycystic Kidney (ADPKD) 08/2005 - 02/2002
1	Infections 01/2023
1	Kidney Diseases (Kidney Disease) 01/2023
1	Hereditary Spherocytosis 10/2021
1	Cystitis 01/2020
1	Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal) 01/2019
1	Dehydration (Water Stress) 01/2019
1	Hyperoxaluria (Oxaluria) 01/2016
1	Cystic Fibrosis (Mucoviscidosis) 08/2011
1	Diastrophic dysplasia 06/2010
1	Choroidal Neovascularization 12/2005
1	Insulin Resistance 12/2005
1	Macular Degeneration (Age-Related Maculopathy) 12/2005
1	Neoplasms (Cancer) 12/2005

Drug/Important Bio-Agent (IBA)

10	CationsIBA 01/2023 - 02/2002
3	AnionsIBA 01/2016 - 03/2008
2	Grammostola spatulata MTx4 proteinIBA 01/2022 - 01/2010
2	OxalatesIBA 06/2010 - 03/2008
1	Ion Channels (Ion Channel)IBA 01/2023
1	proteoliposomesIBA 01/2023
1	AntibodiesIBA 01/2023
1	Lipid Bilayers (Lipid Bilayer)IBA 01/2023
1	Apolipoprotein L1IBA 01/2023
1	Adenosine Triphosphate (ATP)IBA 01/2022
1	AcidsIBA 01/2022
1	Apyrase (ATP Diphosphatase)IBA 01/2022
1	Probenecid (Benemid)FDA LinkGeneric 01/2022
1	Suramin (Suramin Sodium)IBA 01/2022
1	Ketamine FDA LinkGeneric 01/2020
1	Transcription Factors (Transcription Factor)IBA 01/2020
1	TRPC6 Cation ChannelIBA 01/2019
1	senicapocIBA 01/2017
1	Carbon MonoxideIBA 01/2010
1	Peptides (Polypeptides)IBA 03/2008
1	Angiogenesis InhibitorsIBA 12/2005
1	Appetite Depressants (Anorectics)IBA 12/2005
1	squalamineIBA 12/2005
1	Proteins (Proteins, Gene)FDA Link 02/2002